Opioid-related hospital stays have more than doubled over a ten-year period in small metropolitan areas, increasing by 121.6%. Between 2005 and 2014, the rate of inpatient stays in small metropolitan areas increased from 89.6 per 100,000 residents to 198.5 per 100,000 residents. This increase was larger than increases in large metropolitan areas, medium-sized metropolitan areas, and rural areas.

In the analysis, the metropolitan area definitions are as follows:

Large metropolitan area: counties of metropolitan areas with 1 million or more residents. Examples include New York County, New York; Los Angeles County, California . . .

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