Detection of Deception with fMRI: Are we there yet?

October 29, 2009 This brief is written by Daniel D. Langleben, University of Pennsylvania. He writes that a decade of spectacular progress in functional magnetic resonance imaging (fMRI) technology and systems neuroscience research has so far yielded few changes in daily lives. The dearth of clinical applications of this research tool began raising the eyebrows of the public and the research funding agencies. This may be one of the reasons for the growing body of literature suggesting that blood oxygenation level-dependent (BOLD) fMRI of the brain could be sensitive to the differences between lie and truth. The word "differences . . .