21st Century Science: Comparative Effectiveness Research and Personalized Medicine
October 23, 2009 The Lewin paper, "Comparative Effectiveness Research and Personalized Medicine: From Contradiction to Synergy" explains the central challenge of aligning CER and PM. Both are intended to support high-quality, evidence-based decisions for optimal patient care. However, while CER is usually oriented toward evaluating treatment effects across study populations, PM focuses on using individuals, genomic information and other personal traits to inform decisions about their healthcare. Like most other methods used to evaluate healthcare interventions, CER generally focuses on identifying interventions that are effective across a given population. However, interventions that have a statistically significant average treatment . . .
