U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Neurological Disorders and Stroke announces the availability of funding for implementation of the Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Pharmacodynamics and In Vivo Efficacy Studies for Small Molecules and Biologics/Biotechnology Products (R21/R33). The purpose of this grant is to conduct pharmacodynamics, pharmacokinetics, and in vivo efficacy studies to demonstrate that proposed therapeutic agent(s) have sufficient biological activity to warrant further development to treat neurological disorders. Contractors should refer to Section VII, Agency Contacts, in the RFP for information regarding each . . .