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Intrinsic Capacity Framework For Geroscience & Healthspan Trials: A Consensus

May 18, 2026, ARPA-H Convened Working Group published a document with the purpose to provide FDA with expert consensus recommendations on how intrinsic capacity (IC) and its domains might be measured and used as clinical endpoints and enrichment tools in geroscience/healthspan trials. This document will also outline a stepwise validation plan toward potential future use of IC as a broader gerotherapeutic endpoint . . .

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