New Jersey’s J&J Pivots To Early-Stage Alzheimer’s After Failed Trials

Circle Connections: Mergers & Acquisitions Like its rivals, J&J is preparing to pivot from testing drugs in people who already have dementia to early-stage patients, when drugs may have a better shot at working. In November, J&J partnered with Japan's Shionogi to gain access to Shionogi's oral beta secretase, or BACE, inhibitor, a promising new class of drugs that aims to prevent the production of the Alzheimer's-linked protein beta amyloid before it can form toxic clumps in people's brains. While J&J and its partners are retooling bapineuzumab into . . .