Older Adults With Late-In-Life-Depression Age Biologically Older Than Their Chronological Peers & Have Worse Cardiovascular Health

Older adults with depression demonstrate faster biologic aging than their peers. Researchers found that accelerated aging was associated with worse cardiovascular health overall. However, accelerated aging was not associated with depression severity.

People with higher levels of aging-associated proteins were more likely to have high blood pressure, high cholesterol, and multiple medical problems. The accelerated aging was also associated with worse performance on tests of brain health such as working memory and other cognitive skills.

These findings were presented in “Major depression, physical health and molecular senescence markers abnormalities”, by Johanna Seitz-Holland, Benoit H. Mulsant, Charles F. Reynolds . . .