On November 4, 2022, the U.S. Centers for disease Control and Prevention (CDC) published this clinical practice guideline for prescribing opioids for pain. This guideline provides recommendations for clinicians providing pain care, including those prescribing opioids, for outpatients aged ≥18 years. It updates the CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016 and includes recommendations for managing acute (duration of less than one month), subacute (duration of one to three months), and chronic (duration of greater than three months) pain. The recommendations do not apply to pain related to sickle cell disease or cancer or to . . .

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