Greater Apathy, Depression At Parkinson’s Diagnosis Tied To Cognitive Decline

Data suggest that neuropsychiatric symptoms may be valuable in predicting future cognitive decline among those with Parkinson’s disease, a progressive disorder that affects the nervous system and the parts of the body controlled by the nerves.

Individuals with certain comorbid neuropsychiatric symptoms at the time of diagnosis with Parkinson’s disease were more likely to meet the criteria for mild cognitive impairment (MCI).

Depression and anxiety: Those with depression and anxiety showed a progressive decline in four major cognitive domains: memory, visuospatial functions, working memory-executive functions, and attention-processing speed. The odds of MCI were 157% higher among . . .