Dementia Among People Under Age 65 Is Linked To 15 Factors

People under age 65 who develop dementia are more likely to have one or more of 15 factors associated with higher risk of young onset dementia (YOD). The factors include low socioeconomic status, apolipoprotein E status, alcohol use disorder, social isolation, vitamin D deficiency, high C-reactive protein levels, hearing impairment, orthostatic hypotension, stroke, diabetes, heart disease, and depression. People with some alcohol use, higher formal education, and lower physical frailty (as measured by handgrip strength) had a lower incidence of YOD. Genetic factors identified so far account for 5% to 10% of all YOD cases.

Previous research has investigated . . .