Second-Generation Antidepressants for Treating Adult Depression: An Update

In July 2012, a Clinical Research Summary (CRS) was released by the Agency for Healthcare Research and Quality (AHRQ) entitled, Second Generation Antidepressants for Treating Adult Depression; An Update. The CRS discussed the findings of the December 2011 report which updated the findings of the original 2007 report. A review of 248 clinical studies published between 1980 and 2011 were evaluated to compare effectiveness, benefits, and adverse effects of second-generation antidepressants for adults with depression. The purpose of the summary was for clinicians to use when informing patients of their options.

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The summary presents a background for depressive . . .