Among people with end-stage renal disease (ESRD), receiving in-center hemodialysis treatments four or more times per week, rather than three times per week (usual care), may improve their clinical outcomes. A review comparing more frequent and/or longer hemodialysis to usual care was conducted. Low strength of evidence was found for a few outcomes. Note that low strength of evidence means that there is low confidence that the evidence reflects the true effect, and that future research may change the results.

There was low strength of evidence (five studies) that more frequent hemodialysis was associated with lower mortality . . .

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