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The opioid situation in the U.S. gets lots of ink in the popular press because its impact is now extended beyond health policy and into the day-to-day lives of Americans. Opioid-related deaths are up — a county-by-county study of deaths in the U.S. revealed a 200% or more increase in deaths related to substance abuse and mental health in 2,000-plus counties across the United States — and that includes the Appalachian regions of Ohio, Kentucky, and West Virginia, where fatalities went up by more than 1,000% between 1980 and 2014 (see Many . . .

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