Alzheimer’s Disease Causal In Pre-Morbid Mental Health Problems

The pathology behind Alzheimer’s disease (AD) may be a direct cause of emotional and behavioral symptoms. According to a study that included 781 participants with AD biomarkers, when individuals with AD experienced decline in their memory and thinking abilities, they also experienced more neuropsychiatric symptoms.

Greater levels of proteins associated with AD, as indicated by cerebrospinal fluid (CSF) markers, predicted various mental health symptoms, which was only partially explained by cognitive symptoms. That is, the mental health symptoms were not fully explained by response to memory difficulties but may be a direct result of underlying brain changes related to . . .