Cognitive Remediation Plus Transcranial Stimulation Slows Cognitive Decline In At-Risk Adults For Up To Six Years

Combining cognitive remediation (CR) with transcranial direct current stimulation (tDCS) was associated with slower cognitive decline during a follow-up of up to six years in older adults with major depressive disorder that was in remission (rMDD), mild cognitive impairment (MCI), or both. The combined CR and tDCS intervention, which both targeted the prefrontal cortex, was tested in a longitudinal trial that compared the combination of active CR plus active tDCS to a combination of sham interventions. The treatment of CR plus tDCS was effective in slowing cognitive decline in the entire sample and most effective in those with rMDD . . .