In people with dementia and depression, three non-drug therapies were found to be more effective than antidepressants. The three most effective non-antidepressant treatments were: massage and touch therapy, cognitive stimulation with a cholinesterase inhibitor, and cognitive stimulation combined with exercise and social interaction. A total of 10 interventions were associated with a greater reduction in symptoms of depression compared with usual care with antidepressants: Cognitive stimulation: Structures therapy (e.g., one or two sessions per week, for a defined number of hours) with sessions aimed at promoting cognitive function (e.g., orientation, reminiscence, art therapy, games . . .
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