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U.S. Syphilis Cases In Newborns Increase 755% During 2012 To 2022

The number of babies born with syphilis in the United States increased by 755% between 2012 and 2022, from 334 in 2012 and 3,761 in 2022. Syphilis during pregnancy can lead to stillbirth, miscarriage, infant death, and maternal and infant morbidity. In 2022, these cases included 231 stillbirths (6% of cases) and 51 infant deaths (1% of cases).

Between 2005 and 2022, the prevalence of syphilis cases in the United States increased by 555%, from 11.2 per 100,000 in 2005 to 62.2 per 100,000 in 2022. In 2022, about 28% of syphilis cases were infectious . . .

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