Young and middle-aged adults ages 25 to 64 (working age) in the U.S. have been dying at higher rates since 2010 due to drugs overdoses and alcohol (collectively), suicide, and cardiometabolic diseases. In the early-2010s, increases in U.S. life expectancy flattened, and then decreased between 2014 and 2017 for both males and females. Drugs and alcohol were responsible for more than 1.3 million deaths (about 8%) among the working-age population during the 1990 to 2017 study period. While drug-related mortality rates increased in every U.S. state over the study period, the increases . . .
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