The U.S. economic cost of opioid use disorder during 2017 totaled $1 trillion. Of that sum, $471 billion was due to opioid use disorder, and $550 billion was due to fatal opioid overdoses. Approximately 47,600 persons in the United States died from an opioid-involved overdose in 2018, and 2.13 million persons met the diagnostic criteria for an opioid use disorder in 2017. The $471 billion in spending due to opioid use disorder included the following elements: Health care at $26.3 billion Addiction treatment at nearly $3 billion Criminal justice . . .
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